Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- RNA polymerase II, heptapeptide repeat, eukaryotic
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase subunit RPABC5/Rpb10
- Zinc finger, TFIIS-type
- Nucleic acid-binding, OB-fold
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase subunit Rpo5/Rpb5
- RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4
77 more domains
Structure analysis Details
Assembly composition:
hetero 28-mer (preferred)
Assembly name:
DNA-directed RNA polymerase II complex (preferred)
PDBe Complex ID:
PDB-CPX-126927 (preferred)
Entry contents:
28 distinct polypeptide molecules
Macromolecules (28 distinct):
Mediator of RNA polymerase II transcription subunit 6
Molecule details ›
Chain: F
Length: 216 amino acids
Theoretical weight: 24.93 KDa
Source organism: Schizosaccharomyces pombe
UniProt:
Sequence domains: MED6 mediator sub complex component
Length: 216 amino acids
Theoretical weight: 24.93 KDa
Source organism: Schizosaccharomyces pombe
UniProt:
- Canonical:
Q9US45 (Residues: 1-216; Coverage: 100%)
Sequence domains: MED6 mediator sub complex component
Mediator of RNA polymerase II transcription subunit 8
Molecule details ›
Chain: H
Length: 200 amino acids
Theoretical weight: 23.36 KDa
Source organism: Schizosaccharomyces pombe
UniProt:
Sequence domains: Mediator of RNA polymerase II transcription complex subunit 8
Length: 200 amino acids
Theoretical weight: 23.36 KDa
Source organism: Schizosaccharomyces pombe
UniProt:
- Canonical: O94646 (Residues: 1-200; Coverage: 100%)
Sequence domains: Mediator of RNA polymerase II transcription complex subunit 8
Mediator of RNA polymerase II transcription subunit 17
Mediator of RNA polymerase II transcription subunit 18
Mediator of RNA polymerase II transcription subunit 20
Mediator of RNA polymerase II transcription subunit 11
Mediator of RNA polymerase II transcription subunit 22
Mediator of RNA polymerase II transcription subunit 14
Mediator of RNA polymerase II transcription subunit 7
Mediator of RNA polymerase II transcription subunit 21
Mediator of RNA polymerase II transcription subunit 31
Mediator of RNA polymerase II transcription subunit 27
Mediator complex subunit 9
DNA-directed RNA polymerase II subunit rpb1
DNA-directed RNA polymerase II subunit RPB2
DNA-directed RNA polymerase II subunit RPB3
DNA-directed RNA polymerase II subunit rpb4
DNA-directed RNA polymerases I, II, and III subunit RPABC1
DNA-directed RNA polymerases I, II, and III subunit RPABC2
DNA-directed RNA polymerase II subunit rpb7
DNA-directed RNA polymerases I, II, and III subunit RPABC3
DNA-directed RNA polymerase II subunit RPB9
DNA-directed RNA polymerases I, II, and III subunit RPABC5
DNA-directed RNA polymerase II subunit RPB11
DNA-directed RNA polymerases I, II, and III subunit RPABC4
