› 5u2p

X-ray diffraction
1.76Å resolution

The crystal structure of Tp0737 from Treponema pallidum

Released:
DOI: 10.2210/pdb5u2p/pdb
PDB entry 5u2p coloured by chain, front view.
PDB entry 5u2p coloured by chain, side view.
PDB entry 5u2p coloured by chain, top view.
Source organism: Treponema pallidum subsp. pallidum
Primary publication:
Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum.
Brautigam CA, Deka RK, Liu WZ, Tomchick DR, Norgard MV
Protein Sci 26 847-856 (2017)
PMID: 28168761

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166141 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sugar ABC transporter substrate-binding protein Chain: A
Molecule details ›
Chain: A
Length: 428 amino acids
Theoretical weight: 47.72 KDa
Source organism: Treponema pallidum subsp. pallidum
Expression system: Escherichia coli

Ligands and Environments

3 bound ligands:
Ligand BR 1 x BR
Ligand CL 2 x CL
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3121
Unit cell:
a: 55.925Å b: 55.925Å c: 237.632Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.181 0.222
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Possible effects of Treponema pallidum infection on human vascular endothelial cells.
Xie et al. (2022)
4 other articles

1 mention without citation

Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum.
Brautigam et al. (2017)