› 5u4v

X-ray diffraction
2.6Å resolution

pseudoGTPase domain (pG1) of p190RhoGAP-B

Released:
DOI: 10.2210/pdb5u4v/pdb
PDB entry 5u4v coloured by chain, front view.
PDB entry 5u4v coloured by chain, side view.
PDB entry 5u4v coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
p190RhoGAP proteins contain pseudoGTPase domains.
Stiegler AL, Boggon TJ
Nat Commun 8 506 (2017)
PMID: 28894085

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171504 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho GTPase-activating protein 5 Chain: A
Molecule details ›
Chain: A
Length: 176 amino acids
Theoretical weight: 19.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13017 (Residues: 590-763; Coverage: 12%)
Gene names: ARHGAP5, RHOGAP5

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P43
Unit cell:
a: 40.763Å b: 40.763Å c: 95.214Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.246 0.244 0.274
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

MicroRNAs as Potential Targets for Therapeutic Intervention With Metastasis of Non-small Cell Lung Cancer.
Weidle et al. (2019)
9 more

1 mention without citation

p190RhoGAP proteins contain pseudoGTPase domains.
Stiegler et al. (2017)