› 5u75

X-ray diffraction
1.66Å resolution

The structure of Staphylococcal Enterotoxin-like X (SElX), a Unique Superantigen

Released:
DOI: 10.2210/pdb5u75/pdb
Model geometry
Fit model/data
PDB entry 5u75 coloured by chain, front view.
PDB entry 5u75 coloured by chain, side view.
PDB entry 5u75 coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Staphylococcal enterotoxin-like X (SElX) is a unique superantigen with functional features of two major families of staphylococcal virulence factors.
Langley RJ, Ting YT, Clow F, Young PG, Radcliff FJ, Choi JM, Sequeira RP, Holtfreter S, Baker H, Fraser JD
OpenAccess logo PLoS Pathog 13 e1006549 (2017)
PMID: 28880913

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124165 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Enterotoxin-like toxin X Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 19.42 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: G0Z026 (Residues: 36-203; Coverage: 83%)
Gene name: selX
Sequence domains: Staphylococcal/Streptococcal toxin, beta-grasp domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NDG, GAL, SIA, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P65
Unit cell:
a: 92.141Å b: 92.141Å c: 53.418Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.185 0.214
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Basis of Virulence in Enterotoxin-Mediated Staphylococcal Food Poisoning.
Fisher et al. (2018)
5 more

2 mentions without citation

Staphylococcal enterotoxin-like X (SElX) is a unique superantigen with functional features of two major families of staphylococcal virulence factors.
Langley et al. (2017)
1 more