› 5uba

X-ray diffraction
1.54Å resolution

Human RNA Pseudouridylate Synthase Domain Containing 4

Released:
DOI: 10.2210/pdb5uba/pdb
PDB entry 5uba coloured by chain, front view.
PDB entry 5uba coloured by chain, side view.
PDB entry 5uba coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: DONG A, ZENG H, TEMPEL W, Bountra C, Arrowsmith CH, Edwards AM, BROWN PJ, WU H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188415 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pseudouridylate synthase RPUSD4, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 295 amino acids
Theoretical weight: 33.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96CM3 (Residues: 89-365; Coverage: 74%)
Gene name: RPUSD4
Sequence domains: RNA pseudouridylate synthase

Ligands and Environments

3 bound ligands:
Ligand CL 3 x CL
Ligand CA 1 x CA
Ligand UNX 2 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43
Unit cell:
a: 54.189Å b: 54.189Å c: 105.349Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.212
Expression system: Escherichia coli BL21(DE3)

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