› 5ud6

X-ray diffraction
2.4Å resolution

Crystal structure of DHDPS from Cyanidioschyzon merolae with lysine bound

Released:
DOI: 10.2210/pdb5ud6/pdb
Model geometry
Fit model/data
PDB entry 5ud6 coloured by chain, front view.
PDB entry 5ud6 coloured by chain, side view.
PDB entry 5ud6 coloured by chain, top view.
Source organism: Cyanidioschyzon merolae strain 10D
Entry authors: Watkin S, Keown JR, Pearce FG

Function and Biology Details

Reaction catalysed: 
Pyruvate + L-aspartate-4-semialdehyde = (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinate + H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125959 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
4-hydroxy-tetrahydrodipicolinate synthase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 327 amino acids
Theoretical weight: 35.27 KDa
Source organism: Cyanidioschyzon merolae strain 10D
Expression system: Escherichia coli
UniProt:
  • Canonical: M1V4H9 (Residues: 45-354; Coverage: 88%)
Gene name: CYME_CME179C
Sequence domains: Dihydrodipicolinate synthetase family
Structure domains: Aldolase class I

Ligands and Environments

2 bound ligands:
Ligand CA 4 x CA
Ligand LYS 4 x LYS
1 modified residue:
Ligand KPI 4 x KPI

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P21
Unit cell:
a: 81.63Å b: 74.7Å c: 97.55Å
α: 90° β: 103.31° γ: 90°
R-values:
R R work R free
0.214 0.212 0.255
Expression system: Escherichia coli

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