› 5ufi

X-ray diffraction
2.58Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188521 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DCN1-like protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 225 amino acids
Theoretical weight: 26.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96GG9 (Residues: 58-259; Coverage: 78%)
Gene names: DCN1, DCUN1D1, DCUN1L1, RP42, SCCRO
Sequence domains: Cullin binding
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand 8B1 4 x 8B1
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P212121
Unit cell:
a: 62.142Å b: 101.647Å c: 173.521Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.21 0.24
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment.
Li et al. (2021)
13 more

3 mentions without citation

Anticancer drug discovery by targeting cullin neddylation.
Yu et al. (2020)
2 more