5umo

X-ray diffraction
2.26Å resolution

STRUCTURE OF EXTRACELLULAR SIGNAL-REGULATED KINASE

Released:
Source organism: Rattus norvegicus

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-158941 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 364 amino acids
Theoretical weight: 42.16 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P63086 (Residues: 4-354; Coverage: 98%)
Gene names: Erk2, Mapk, Mapk1, Prkm1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 49.32Å b: 72.42Å c: 61.25Å
α: 90° β: 109.5° γ: 90°
R-values:
R R work R free
0.15 0.147 0.202
Expression system: Escherichia coli BL21(DE3)