› 5uy6

X-ray diffraction
1.7Å resolution

Crystal Structure of the Human CAMKK2B

Released:
DOI: 10.2210/pdb5uy6/pdb
PDB entry 5uy6 coloured by chain, front view.
PDB entry 5uy6 coloured by chain, side view.
PDB entry 5uy6 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Counago RM, Dewry D, Bountra C, Arruda P, Edwards AM, Gileadi O, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188735 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase kinase 2 Chain: A
Molecule details ›
Chain: A
Length: 291 amino acids
Theoretical weight: 33.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96RR4 (Residues: 161-449; Coverage: 49%)
Gene names: CAMKK2, CAMKKB, KIAA0787
Sequence domains: Protein kinase domain

Ligands and Environments

1 bound ligand:
Ligand 8R4 1 x 8R4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P43212
Unit cell:
a: 73.324Å b: 73.324Å c: 121.964Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.16 0.182
Expression system: Escherichia coli BL21(DE3)

Quick links