Function and Biology Details
Reactions catalysed:
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
ORF1ab (preferred)
PDBe Complex ID:
PDB-CPX-125469 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ORF1ab
Molecule details ›
Chain: A
Length: 324 amino acids
Theoretical weight: 36.05 KDa
Source organism: Human betacoronavirus 2c EMC/2012
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Coronavirus papain-like peptidase
Structure domains:
Length: 324 amino acids
Theoretical weight: 36.05 KDa
Source organism: Human betacoronavirus 2c EMC/2012
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
K0BWD0 (Residues: 1480-1803; Coverage: 5%)
Sequence domains: Coronavirus papain-like peptidase
Structure domains:
