› 5v86

X-ray diffraction
1.37Å resolution

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133016 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DCN1-like protein 1; Endolysin Chain: A
Molecule details ›
Chain: A
Length: 384 amino acids
Theoretical weight: 44.18 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00720 (Residues: 1-164; Coverage: 100%)
  • Canonical: Q96GG9 (Residues: 62-259; Coverage: 76%)
Gene names: DCN1, DCUN1D1, DCUN1L1, E, RP42, SCCRO
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand 8ZA 1 x 8ZA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 35.045Å b: 96.849Å c: 59.302Å
α: 90° β: 105.83° γ: 90°
R-values:
R R work R free
0.157 0.155 0.195
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

16 review citations

The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway.
Baird et al. (2020)
15 more

4 mentions without citation

Anticancer drug discovery by targeting cullin neddylation.
Yu et al. (2020)
3 more