› 5vfm

X-ray diffraction
2.06Å resolution

Crystal structure of BnSP-7 from Bothrops pauloensis complexed with p-coumaric acid

Released:
DOI: 10.2210/pdb5vfm/pdb
Model geometry
Fit model/data
PDB entry 5vfm coloured by chain, front view.
PDB entry 5vfm coloured by chain, side view.
PDB entry 5vfm coloured by chain, top view.
Source organism: Bothrops pauloensis
Primary publication:
Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins.
de Lima LFG, Borges RJ, Viviescas MA, Fernandes CAH, Fontes MRM
Biochimie 142 11-21 (2017)
PMID: 28751219

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191519 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Basic phospholipase A2 homolog BnSP-7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 121 amino acids
Theoretical weight: 13.75 KDa
Source organism: Bothrops pauloensis
UniProt:
  • Canonical: Q9IAT9 (Residues: 3-121; Coverage: 98%)
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain

Ligands and Environments

3 bound ligands:
Ligand ME2 2 x ME2
Ligand SO4 9 x SO4
Ligand HC4 1 x HC4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: LNLS BEAMLINE W01B-MX2
Spacegroup: P21
Unit cell:
a: 45.79Å b: 58.039Å c: 58.01Å
α: 90° β: 96.04° γ: 90°
R-values:
R R work R free
0.176 0.171 0.214

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Citations

1 review citation

Secreted Phospholipases A₂ from Animal Venoms in Pain and Analgesia.
Zambelli et al. (2017)
3 other articles