5vkk

X-ray diffraction
2.01Å resolution

Crystal structure of Fab fragment of anti-CD22 Epratuzumab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-179926 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chains: A, H
Molecule details ›
Chains: A, H
Length: 219 amino acids
Theoretical weight: 23.74 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6N089 (Residues: 20-245; Coverage: 48%)
Gene name: DKFZp686P15220
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chains: B, L
Molecule details ›
Chains: B, L
Length: 219 amino acids
Theoretical weight: 24.05 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8TCD0 (Residues: 21-52, 53-116, 117-239; Coverage: 99%)
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P1
Unit cell:
a: 56.712Å b: 61.564Å c: 65.285Å
α: 71.81° β: 81.07° γ: 75.95°
R-values:
R R work R free
0.213 0.212 0.237
Expression system: Homo sapiens