5vms

Electron Microscopy
3.7Å resolution

CryoEM structure of Xenopus KCNQ1 channel

Released:
Source organisms:
Related structures: EMD-8712

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-143995 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Potassium voltage-gated channel subfamily KQT member 1 Chain: A
Molecule details ›
Chain: A
Length: 548 amino acids
Theoretical weight: 62.66 KDa
Source organism: Xenopus laevis
Expression system: Homo sapiens
UniProt:
  • Canonical: P70057 (Residues: 66-610; Coverage: 84%)
Gene names: kcnq1, kvlqt1
Sequence domains:
Calmodulin-1 Chain: B
Molecule details ›
Chain: B
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DP23 (Residues: 1-149; Coverage: 100%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-8712
Expression system: Homo sapiens