Function and Biology Details
Reactions catalysed:
Acetyl-CoA + H(2)O + glyoxylate = (S)-malate + CoA
(S)-malyl-CoA + H(2)O = (S)-malate + CoA
(3S)-citramalyl-CoA = acetyl-CoA + pyruvate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo trimer (preferred)
Assembly name:
Citramalyl-CoA lyase, mitochondrial (preferred)
PDBe Complex ID:
PDB-CPX-185345 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Citramalyl-CoA lyase, mitochondrial
Molecule details ›
Chains: A, B, C
Length: 325 amino acids
Theoretical weight: 36.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: HpcH/HpaI aldolase/citrate lyase family
Length: 325 amino acids
Theoretical weight: 36.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q8N0X4 (Residues: 30-340; Coverage: 92%)
Sequence domains: HpcH/HpaI aldolase/citrate lyase family
