5w1o

X-ray diffraction
2.8Å resolution

Crystal Structure of HPV16 L1 Pentamer Bound to Heparin Oligosaccharides

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
PDBe Complex ID:
PDB-CPX-182413 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Major capsid protein L1 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 427 amino acids
Theoretical weight: 47.55 KDa
Source organism: Human papillomavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q81007 (Residues: 12-394, 429-465; Coverage: 85%)
Gene name: L1
Sequence domains: L1 (late) protein
Structure domains: Major capsid L1 (late) superfamily, Papillomavirus

Ligands and Environments

Carbohydrate polymer : NEW Components: JHM, IDS
Carbohydrate polymer : NEW Components: JHM, IDS
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P21
Unit cell:
a: 96.62Å b: 101.252Å c: 128.182Å
α: 90° β: 90.63° γ: 90°
R-values:
R R work R free
0.226 0.224 0.27
Expression system: Escherichia coli