5w1x

X-ray diffraction
3.37Å resolution

Crystal Structure of Humanpapillomavirus18 (HPV18) Capsid L1 Pentamers Bound to Heparin Oligosaccharides

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
PDBe Complex ID:
PDB-CPX-139234 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (5 distinct):
Major capsid protein L1 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O
Length: 427 amino acids
Theoretical weight: 47.48 KDa
Source organism: human papillomavirus 18
Expression system: Escherichia coli
UniProt:
  • Canonical: P06794 (Residues: 82-465, 499-535; Coverage: 74%)
Gene name: L1
Sequence domains: L1 (late) protein
Structure domains: Major capsid L1 (late) superfamily, Papillomavirus

Ligands and Environments

Carbohydrate polymer : NEW Components: JHM, IDS
Carbohydrate polymer : NEW Components: JHM, IDS
Carbohydrate polymer : NEW Components: JHM, IDS
Carbohydrate polymer : NEW Components: JHM, IDS
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P1
Unit cell:
a: 80.993Å b: 106.49Å c: 237.661Å
α: 88.46° β: 85.75° γ: 69.02°
R-values:
R R work R free
0.174 0.171 0.234
Expression system: Escherichia coli