› 5w23

X-ray diffraction
3.4Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-230770 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fusion glycoprotein F0 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 568 amino acids
Theoretical weight: 63.11 KDa
Source organism: Human respiratory syncytial virus A2
Expression system: Homo sapiens
UniProt:
  • Canonical: P03420 (Residues: 1-513; Coverage: 89%)
Gene name: F
Sequence domains: Fusion glycoprotein F0
5C4 Fab heavy chain Chains: H, I, J
Molecule details ›
Chains: H, I, J
Length: 249 amino acids
Theoretical weight: 26.68 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins
5C4 Fab light chain Chains: L, M, N
Molecule details ›
Chains: L, M, N
Length: 241 amino acids
Theoretical weight: 26.73 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand ZN 8 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P41212
Unit cell:
a: 183.36Å b: 183.36Å c: 275.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.239
Expression system: Homo sapiens

Quick links

Citations

6 review citations

Viral-Induced Enhanced Disease Illness.
Smatti et al. (2018)
5 more

7 mentions without citation

Antibody Epitopes of Pneumovirus Fusion Proteins.
Huang et al. (2019)
6 more