5w9h

Electron Microscopy
4Å resolution

MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-207967 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, D, G, p, q, r
Molecule details ›
Chains: A, D, G, p, q, r
Length: 1329 amino acids
Theoretical weight: 146.33 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: K9N5Q8 (Residues: 1-1291; Coverage: 95%)
Gene names: 3, S
Sequence domains:
G4 VH Chains: B, E, H
Molecule details ›
Chains: B, E, H
Length: 233 amino acids
Theoretical weight: 25.31 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
G4 VL Chains: C, F, I
Molecule details ›
Chains: C, F, I
Length: 218 amino acids
Theoretical weight: 23.87 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-8783
Expression system: Homo sapiens