› 5wfb

X-ray diffraction
1.38Å resolution

Tepsin tENTH domain 1-136.

Released:
DOI: 10.2210/pdb5wfb/pdb
PDB entry 5wfb coloured by chain, front view.
PDB entry 5wfb coloured by chain, side view.
PDB entry 5wfb coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure and evolution of ENTH and VHS/ENTH-like domains in tepsin.
Archuleta TL, Frazier MN, Monken AE, Kendall AK, Harp J, McCoy AJ, Creanza N, Jackson LP
Traffic 18 590-603 (2017)
PMID: 28691777

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188645 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AP-4 complex accessory subunit Tepsin Chains: A, B
Molecule details ›
Chains: A, B
Length: 145 amino acids
Theoretical weight: 15.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96N21 (Residues: 1-140; Coverage: 27%)
Gene names: C17orf56, ENTHD2, TEPSIN
Sequence domains: ENTH domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2221
Unit cell:
a: 80.87Å b: 84.75Å c: 80.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.156 0.185
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Cargo Sorting at the trans-Golgi Network for Shunting into Specific Transport Routes: Role of Arf Small G Proteins and Adaptor Complexes.
Tan et al. (2019)
2 more