Function and Biology Details
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Optineurin and Ubiquitin (preferred)
PDBe Complex ID:
PDB-CPX-143387 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 17.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ubiquitin family
Length: 152 amino acids
Theoretical weight: 17.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
- Canonical:
P0CG48 (Residues: 533-684; Coverage: 22%)
Sequence domains: Ubiquitin family
Optineurin
Molecule details ›
Chains: C, D, E, F
Length: 97 amino acids
Theoretical weight: 11.17 KDa
Source organism: Mus musculus
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
Length: 97 amino acids
Theoretical weight: 11.17 KDa
Source organism: Mus musculus
Expression system: Escherichia coli K-12
UniProt:
- Canonical: Q8K3K8 (Residues: 417-513; Coverage: 17%)
Sequence domains: Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRF BEAMLINE BL17U
Spacegroup:
P43
Expression system: Escherichia coli K-12
