› 5wsq

X-ray diffraction
1.05Å resolution

Crystal structure of C-Hg-T pair containing DNA duplex

Released:
DOI: 10.2210/pdb5wsq/pdb
PDB entry 5wsq coloured by chain, front view.
PDB entry 5wsq coloured by chain, side view.
PDB entry 5wsq coloured by chain, top view.
Source organism: unidentified
Primary publication:
Flexibility and stabilization of HgII-mediated C:T and T:T base pairs in DNA duplex.
Liu H, Cai C, Haruehanroengra P, Yao Q, Chen Y, Yang C, Luo Q, Wu B, Li J, Ma J, Sheng J, Gan J
Nucleic Acids Res 45 2910-2918 (2017)
PMID: 27998930

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-119359 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*GP*CP*CP*CP*GP*TP*GP*C)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 8 nucleotides
Theoretical weight: 2.4 KDa
Source organism: unidentified
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand HG 2 x HG
Ligand PDO 1 x PDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P21212
Unit cell:
a: 37.848Å b: 51.138Å c: 21.593Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 0.155 0.175
Expression system: Not provided

Quick links

Citations

13 citation in other articles

Crystal structure of a DNA duplex containing four Ag(i) ions in consecutive dinuclear Ag(i)-mediated base pairs: 4-thiothymine-2Ag(i)-4-thiothymine.
Kondo et al. (2017)
12 more

2 mentions without citation

A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding.
Satange et al. (2018)
1 more