› 5wud

X-ray diffraction
1.9Å resolution

Structural basis for conductance through TRIC cation channels

Released:
DOI: 10.2210/pdb5wud/pdb
PDB entry 5wud coloured by chain, front view.
PDB entry 5wud coloured by chain, side view.
PDB entry 5wud coloured by chain, top view.
Source organism: Sulfolobus acidocaldarius
Primary publication:
Structural basis for conductance through TRIC cation channels.
Su M, Gao F, Yuan Q, Mao Y, Li DL, Guo Y, Yang C, Wang XH, Bruni R, Kloss B, Zhao H, Zeng Y, Zhang FB, Marks AR, Hendrickson WA, Chen YH
Nat Commun 8 15103 (2017)
PMID: 28524849

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102745 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycine transporter domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 237 amino acids
Theoretical weight: 25.72 KDa
Source organism: Sulfolobus acidocaldarius
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: A0A0U3H1E6 (Residues: 1-207; Coverage: 100%)
Gene names: ATY89_00310, ATZ20_03355
Sequence domains: Glycine transporter

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P63
Unit cell:
a: 64.613Å b: 64.613Å c: 80.955Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.189 0.187 0.22
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

Quick links

Citations

1 review citation

TRIC-A regulates intracellular Ca2+ homeostasis in cardiomyocytes.
Zhou et al. (2021)
7 other articles

1 mention without citation

Structural basis for conductance through TRIC cation channels.
Su et al. (2017)