› 5xjj

X-ray diffraction
2.9Å resolution

Crystal structure of a MATE family protein

Released:
DOI: 10.2210/pdb5xjj/pdb
PDB entry 5xjj coloured by chain, front view.
PDB entry 5xjj coloured by chain, side view.
PDB entry 5xjj coloured by chain, top view.
Source organism: Camelina sativa
Primary publication:
Crystal Structure of a Plant Multidrug and Toxic Compound Extrusion Family Protein.
Tanaka Y, Iwaki S, Tsukazaki T
Structure 25 1455-1460.e2 (2017)
PMID: 28877507

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104182 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein DETOXIFICATION Chain: A
Molecule details ›
Chain: A
Length: 455 amino acids
Theoretical weight: 49.64 KDa
Source organism: Camelina sativa
Expression system: Komagataella pastoris
UniProt:
  • Canonical: A0A2D0TCI5 (Residues: 1-455; Coverage: 100%)
Sequence domains: MatE

Ligands and Environments

1 bound ligand:
Ligand OLC 1 x OLC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Spacegroup: P212121
Unit cell:
a: 60.71Å b: 69.89Å c: 117.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.239 0.296
Expression system: Komagataella pastoris

Quick links

Citations

4 review citations

Membrane transporters: the key drivers of transport of secondary metabolites in plants.
Gani et al. (2021)
3 more

2 mentions without citation

Principles of Alternating Access in Multidrug and Toxin Extrusion (MATE) Transporters.
Claxton et al. (2021)
1 more