› 5xjk

Solution NMR

NMR Structure and Localization of a Large Fragment of the SARS-CoV Fusion Protein: Implications in Viral Cell Fusion

Released:
DOI: 10.2210/pdb5xjk/pdb
PDB entry 5xjk coloured by chain, ensemble of 20 models, front view.
PDB entry 5xjk coloured by chain, ensemble of 20 models, side view.
PDB entry 5xjk coloured by chain, ensemble of 20 models, top view.
Source organism: Severe acute respiratory syndrome-related coronavirus
Primary publication:
NMR structure and localization of a large fragment of the SARS-CoV fusion protein: Implications in viral cell fusion.
Mahajan M, Chatterjee D, Bhuvaneswari K, Pillay S, Bhattacharjya S
Biochim Biophys Acta Biomembr 1860 407-415 (2018)
PMID: 28988778

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157797 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spike protein S2' Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.54 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: P59594 (Residues: 758-821; Coverage: 5%)
Gene names: 2, S

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 31%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

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Citations

3 review citations

Host-membrane interacting interface of the SARS coronavirus envelope protein: Immense functional potential of C-terminal domain.
Mukherjee et al. (2020)
2 more

1 mention without citation

NMR structure and localization of a large fragment of the SARS-CoV fusion protein: Implications in viral cell fusion.
Mahajan et al. (2018)