Function and Biology Details
Reaction catalysed:
2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NAD(P)(+) = 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185828 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
Molecule details ›
Chains: A, B, C, D, E, F
Length: 240 amino acids
Theoretical weight: 26.15 KDa
Source organism: Methanosarcina mazei Go1
Expression system: Escherichia coli
UniProt:
Sequence domains: RibD C-terminal domain
Structure domains: Dihydrofolate Reductase, subunit A
Length: 240 amino acids
Theoretical weight: 26.15 KDa
Source organism: Methanosarcina mazei Go1
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8PYN5 (Residues: 1-228; Coverage: 100%)
Sequence domains: RibD C-terminal domain
Structure domains: Dihydrofolate Reductase, subunit A
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
NSRRC BEAMLINE BL13B1
Spacegroup:
R3
Expression system: Escherichia coli
