› 5y70

Solution NMR

NMR structure of KMP11 in DPC micelle

Released:
DOI: 10.2210/pdb5y70/pdb
PDB entry 5y70 coloured by chain, ensemble of 15 models, front view.
PDB entry 5y70 coloured by chain, ensemble of 15 models, side view.
PDB entry 5y70 coloured by chain, ensemble of 15 models, top view.
Source organism: Trypanosoma brucei brucei
Primary publication:
Kinetoplastid membrane protein-11 adopts a four-helix bundle fold in DPC micelle.
Lim LZ, Ee S, Fu J, Tan Y, He CY, Song J
FEBS Lett 591 3793-3804 (2017)
PMID: 29082514

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159567 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinetoplastid membrane protein 11 Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 12.07 KDa
Source organism: Trypanosoma brucei brucei
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P69300 (Residues: 1-92; Coverage: 100%)
Gene names: KMP-11/1, KMP-11/2, KMP-11/3, KMP-11/4
Sequence domains: Kinetoplastid membrane protein 11

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 34%
Refinement method: molecular dynamics
Expression system: Escherichia coli K-12

Quick links

Citations

2 mentions without citation

In silico Design of an Epitope-Based Vaccine Ensemble for Chagas Disease.
Michel-Todó et al. (2019)
1 more