› 5y7l

Solution NMR

Solution structure of Hbeta4 extracellular loop of BK potassium channel

Released:
DOI: 10.2210/pdb5y7l/pdb
PDB entry 5y7l coloured by chain, ensemble of 20 models, front view.
PDB entry 5y7l coloured by chain, ensemble of 20 models, side view.
PDB entry 5y7l coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of extracellular loop of human β4 subunit of BK channel and its biological implication on ChTX sensitivity.
Wang Y, Lan W, Yan Z, Gao J, Liu X, Wang S, Guo X, Wang C, Zhou H, Ding J, Cao C
Sci Rep 8 4571 (2018)
PMID: 29545539

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183224 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-activated potassium channel subunit beta-4 Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 14.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86W47 (Residues: 45-166; Coverage: 58%)
Gene name: KCNMB4
Sequence domains: Calcium-activated potassium channel, beta subunit

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Molecular structures of the human Slo1 K+ channel in complex with β4.
Tao et al. (2019)
2 more

1 mention without citation

Solution structure of extracellular loop of human β4 subunit of BK channel and its biological implication on ChTX sensitivity.
Wang et al. (2018)