› 5y9e

X-ray diffraction
2.04Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150769 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major capsid protein L1 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 490 amino acids
Theoretical weight: 55.25 KDa
Source organism: human papillomavirus 58
Expression system: Escherichia coli
UniProt:
  • Canonical: P26535 (Residues: 36-524; Coverage: 93%)
Gene name: L1
Sequence domains: L1 (late) protein
Structure domains: Major capsid L1 (late) superfamily, Papillomavirus

Ligands and Environments

2 bound ligands:
Ligand GOL 20 x GOL
Ligand MG 29 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: C2
Unit cell:
a: 187.213Å b: 101.804Å c: 136.195Å
α: 90° β: 95.68° γ: 90°
R-values:
R R work R free
0.171 0.168 0.198
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers.
Nooraei et al. (2021)
2 more

5 mentions without citation

Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Li et al. (2018)
4 more