› 5y9m

X-ray diffraction
2.01Å resolution

Crystal structure of CK2a2 form 3

Released:
DOI: 10.2210/pdb5y9m/pdb
PDB entry 5y9m coloured by chain, front view.
PDB entry 5y9m coloured by chain, side view.
PDB entry 5y9m coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of human CK2α2 in new crystal forms arising from a subtle difference in salt concentration.
Tsuyuguchi M, Nakaniwa T, Kinoshita T
Acta Crystallogr F Struct Biol Commun 74 288-293 (2018)
PMID: 29717996

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148708 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase II subunit alpha' Chains: A, X
Molecule details ›
Chains: A, X
Length: 339 amino acids
Theoretical weight: 40.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19784 (Residues: 1-334; Coverage: 95%)
Gene names: CK2A2, CSNK2A2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand NIO 2 x NIO
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Spacegroup: P212121
Unit cell:
a: 72.766Å b: 92.052Å c: 102.891Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.205
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Protein Kinase CK2α', More than a Backup of CK2α.
Montenarh et al. (2023)
1 other article

1 mention without citation

Crystal structures of human CK2α2 in new crystal forms arising from a subtle difference in salt concentration.
Tsuyuguchi et al. (2018)