5yd3

X-ray diffraction
1.35Å resolution

Crystal structure of the scFv antibody 4B08 with epitope peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-208459 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig kappa chain V-II region 7S34.1 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 251 amino acids
Theoretical weight: 26.75 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P01630 (Residues: 1-112; Coverage: 99%)
Sequence domains: Immunoglobulin V-set domain
C-C chemokine receptor type 5 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 9 amino acids
Theoretical weight: 1.1 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P51681 (Residues: 11-19; Coverage: 3%)
Gene names: CCR5, CMKBR5

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P21
Unit cell:
a: 80.48Å b: 72.97Å c: 86.99Å
α: 90° β: 114.3° γ: 90°
R-values:
R R work R free
0.136 0.136 0.184
Expression systems:
  • Escherichia coli BL21
  • Not provided