5yel

X-ray diffraction
2.96Å resolution

Crystal structure of CTCF ZFs6-11-gb7CSE

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-119434 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Transcriptional repressor CTCF Chains: A, B
Molecule details ›
Chains: A, B
Length: 176 amino acids
Theoretical weight: 20.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P49711 (Residues: 405-580; Coverage: 24%)
Gene name: CTCF
Sequence domains: Zinc finger, C2H2 type
DNA (26-MER) Chains: D, F
Molecule details ›
Chains: D, F
Length: 26 nucleotides
Theoretical weight: 7.94 KDa
Source organism: synthetic construct
Expression system: Not provided
DNA (26-MER) Chains: C, E
Molecule details ›
Chains: C, E
Length: 26 nucleotides
Theoretical weight: 8.03 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: C2
Unit cell:
a: 190.993Å b: 69.631Å c: 84.445Å
α: 90° β: 116.25° γ: 90°
R-values:
R R work R free
0.269 0.268 0.286
Expression systems:
  • Escherichia coli K-12
  • Not provided