› 5yfg

Solution NMR

SOLUTION STRUCTURE OF HUMAN MOG1

Released:
DOI: 10.2210/pdb5yfg/pdb
PDB entry 5yfg coloured by chain, ensemble of 20 models, front view.
PDB entry 5yfg coloured by chain, ensemble of 20 models, side view.
PDB entry 5yfg coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation.
Bao X, Liu H, Liu X, Ruan K, Zhang Y, Zhang Z, Hu Q, Liu Y, Akram S, Zhang J, Gong Q, Wang W, Yuan X, Li J, Zhao L, Dou Z, Tian R, Yao X, Wu J, Shi Y
J Mol Cell Biol 10 18-32 (2018)
PMID: 29040603

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ran guanine nucleotide release factor Chain: A
Molecule details ›
Chain: A
Length: 194 amino acids
Theoretical weight: 21.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HD47 (Residues: 1-186; Coverage: 100%)
Gene names: HSPC165, HSPC236, MDS5, MOG1, RANGNRF, RANGRF
Sequence domains: Ran-interacting Mog1 protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 66%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Protein acetylation and deacetylation: An important regulatory modification in gene transcription (Review).
Xia et al. (2020)
4 more

2 mentions without citation

Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation.
Bao et al. (2018)
1 more