› 5yks

X-ray diffraction
2.9Å resolution

Crystal structure of sucrose nonfermenting-related kinase (SNRK)

Released:
DOI: 10.2210/pdb5yks/pdb
PDB entry 5yks coloured by chain, front view.
PDB entry 5yks coloured by chain, side view.
PDB entry 5yks coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the kinase and UBA domains of SNRK reveals a distinct UBA binding mode in the AMPK family.
Wang YL, Wang J, Chen X, Wang ZX, Wu JW
Biochem Biophys Res Commun 495 1-6 (2018)
PMID: 29061304

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192561 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SNF-related serine/threonine-protein kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 377 amino acids
Theoretical weight: 42.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NRH2 (Residues: 1-356; Coverage: 47%)
Gene names: KIAA0096, SNFRK, SNRK
Sequence domains: Protein kinase domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P212121
Unit cell:
a: 91.92Å b: 99.075Å c: 118.656Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.222 0.267
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Sensing of Abiotic Stress and Ionic Stress Responses in Plants.
Zhang et al. (2018)
1 more