5z8y

X-ray diffraction
3.4Å resolution

Crystal structure of human LRRTM2 in complex with Neurexin 1beta

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-128890 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Leucine-rich repeat transmembrane neuronal protein 2 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 346 amino acids
Theoretical weight: 39.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O43300 (Residues: 34-371; Coverage: 70%)
Gene names: KIAA0416, LRRN2, LRRTM2
Sequence domains: Leucine rich repeat
Structure domains: Ribonuclease Inhibitor
Neurexin-1-beta Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 193 amino acids
Theoretical weight: 20.95 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P58400 (Residues: 86-296; Coverage: 43%)
Gene name: NRXN1
Sequence domains: Laminin G domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P1
Unit cell:
a: 99.184Å b: 99.858Å c: 109.633Å
α: 91.3° β: 91.2° γ: 116.47°
R-values:
R R work R free
0.21 0.209 0.241
Expression system: Homo sapiens