Function and Biology Details
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Helicase, C-terminal domain-like
- P-loop containing nucleoside triphosphate hydrolase
- Helicase superfamily 1/2, ATP-binding domain
- ATP-dependent RNA helicase DEAD-box, conserved site
- DEAD/DEAH box helicase domain
- ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain
- RNA helicase, DEAD-box type, Q motif
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Eukaryotic initiation factor 4A-I and RNA (preferred)
PDBe Complex ID:
PDB-CPX-158102 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Eukaryotic initiation factor 4A-I
Molecule details ›
Chain: A
Length: 394 amino acids
Theoretical weight: 44.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 394 amino acids
Theoretical weight: 44.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P60842 (Residues: 19-406; Coverage: 96%)
Sequence domains:
