› 5zju

X-ray diffraction
2.8Å resolution

Crystal structure of in vitro expressed and assembled PCV2 Virus-like Particle

Released:
DOI: 10.2210/pdb5zju/pdb
PDB entry 5zju coloured by chain, front view.
PDB entry 5zju coloured by chain, side view.
PDB entry 5zju coloured by chain, top view.
Source organism: Porcine circovirus 2
Primary publication:
Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitope.
Mo X, Li X, Yin B, Deng J, Tian K, Yuan A
PLoS Pathog 15 e1007562 (2019)
PMID: 30822338

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124148 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein Chains: 1, 2, 3, 4, 5, 6, 7, 8, 9, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v, w, x, y
Molecule details ›
Chains: 1, 2, 3, 4, 5, 6, 7, 8, 9, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v, w, x, y
Length: 209 amino acids
Theoretical weight: 24.13 KDa
Source organism: Porcine circovirus 2
Expression system: Escherichia coli
UniProt:
  • Canonical: G0Y2B2 (Residues: 45-233; Coverage: 81%)
Gene name: cap
Sequence domains: Circovirus capsid protein
Structure domains: Circovirus capsid protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL17A
Spacegroup: P21
Unit cell:
a: 194.116Å b: 201.877Å c: 231.281Å
α: 90° β: 90.72° γ: 90°
R-values:
R R work R free
0.166 0.163 0.224
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Advances in Crosstalk between Porcine Circoviruses and Host.
Niu et al. (2022)
16 other articles

3 mentions without citation

Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitope.
Mo et al. (2019)
2 more