› 5zza

X-ray diffraction
1.53Å resolution

OdinProfilin/Rabbit Actin Complex

Released:
DOI: 10.2210/pdb5zza/pdb
PDB entry 5zza coloured by chain, front view.
PDB entry 5zza coloured by chain, side view.
PDB entry 5zza coloured by chain, top view.
Source organisms:
Primary publication:
Genomes of Asgard archaea encode profilins that regulate actin.
Akıl C, Robinson RC
Nature 562 439-443 (2018)
PMID: 30283132

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-103656 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Odin profilin Chain: P
Molecule details ›
Chain: P
Length: 121 amino acids
Theoretical weight: 12.81 KDa
Source organism: Candidatus Odinarchaeum yellowstonii
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A1Q9N7W7 (Residues: 1-119; Coverage: 100%)
Gene name: OdinLCB4_14170
Actin, alpha skeletal muscle Chain: A
Molecule details ›
Chain: A
Length: 373 amino acids
Theoretical weight: 41.63 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 5-377; Coverage: 99%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand LAB 2 x LAB
Ligand ATP 1 x ATP
Ligand CA 1 x CA
1 modified residue:
Ligand HIC 1 x HIC

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P21
Unit cell:
a: 54.079Å b: 70.669Å c: 77.717Å
α: 90° β: 101.13° γ: 90°
R-values:
R R work R free
0.152 0.15 0.179
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Diversity, ecology and evolution of Archaea.
Baker et al. (2020)
14 more