› 6a7u

X-ray diffraction
2.6Å resolution

Crystal structure of histone H2A.Bbd-H2B dimer

Released:
DOI: 10.2210/pdb6a7u/pdb
PDB entry 6a7u coloured by chain, front view.
PDB entry 6a7u coloured by chain, side view.
PDB entry 6a7u coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the histone heterodimer containing histone variant H2A.Bbd.
Dai L, Xie X, Zhou Z
Biochem Biophys Res Commun 503 1786-1791 (2018)
PMID: 30064909

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143038 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histone H2A-Bbd type 2/3; Histone H2B type 2-E Chain: A
Molecule details ›
Chain: A
Length: 240 amino acids
Theoretical weight: 26.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: Q16778 (Residues: 1-126; Coverage: 100%)
  • Canonical: P0C5Z0 (Residues: 2-115; Coverage: 99%)
Gene names: H2AB2, H2AB3, H2ABBD, H2AFB, H2AFB2, H2AFB3, H2BC21, H2BFQ, HIST2H2BE
Sequence domains: Core histone H2A/H2B/H3/H4
Structure domains: Histone, subunit A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: C2221
Unit cell:
a: 61.64Å b: 141.91Å c: 56.91Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.235 0.263
Expression system: Escherichia coli K-12

Quick links

Citations

2 review citations

Histone variants at a glance.
Talbert et al. (2021)
1 more

2 mentions without citation

Segmental and site-specific isotope labelling strategies for structural analysis of posttranslationally modified proteins.
Vogl et al. (2021)
1 more