› 6adr

Electron Microscopy
3.38Å resolution

Anthrax Toxin Receptor 1-bound the Seneca Valley Virus in neutral conditions

Released:
DOI: 10.2210/pdb6adr/pdb
PDB entry 6adr coloured by chain, front view.
PDB entry 6adr coloured by chain, side view.
PDB entry 6adr coloured by chain, top view.
Source organisms:
Primary publication:
Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1.
Cao L, Zhang R, Liu T, Sun Z, Hu M, Sun Y, Cheng L, Guo Y, Fu S, Hu J, Li X, Yu C, Wang H, Chen H, Li X, Fry EE, Stuart DI, Qian P, Lou Z, Rao Z
Proc Natl Acad Sci U S A 115 13087-13092 (2018)
PMID: 30514821
Related structures: EMD-9611

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 300-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166408 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
VP1 Chain: A
Molecule details ›
Chain: A
Length: 258 amino acids
Theoretical weight: 28.49 KDa
Source organism: Senecavirus A
Structure domains: Jelly Rolls
VP3 Chain: C
Molecule details ›
Chain: C
Length: 239 amino acids
Theoretical weight: 26.39 KDa
Source organism: Senecavirus A
Structure domains: Jelly Rolls
vp2 Chain: B
Molecule details ›
Chain: B
Length: 267 amino acids
Theoretical weight: 29.84 KDa
Source organism: Senecavirus A
Structure domains: Jelly Rolls
VP4 Chain: D
Molecule details ›
Chain: D
Length: 71 amino acids
Theoretical weight: 7.39 KDa
Source organism: Senecavirus A
Anthrax toxin receptor 1 Chain: R
Molecule details ›
Chain: R
Length: 185 amino acids
Theoretical weight: 21.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9H6X2 (Residues: 38-220; Coverage: 34%)
Gene names: ANTXR1, ATR, TEM8
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.38Å
Relevant EMDB volumes: EMD-9611
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Molecular profiles of small cell lung cancer subtypes: therapeutic implications.
Schwendenwein et al. (2021)
2 more

1 mention without citation

Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1.
Cao et al. (2018)