› 6aw1

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-154049 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carcinoembryonic antigen-related cell adhesion molecule 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 109 amino acids
Theoretical weight: 12.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P40198 (Residues: 34-141; Coverage: 49%)
Gene names: CD66D, CEACAM3, CGM1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

4 bound ligands:
Ligand GOL 4 x GOL
Ligand CL 1 x CL
Ligand SO4 1 x SO4
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: I4122
Unit cell:
a: 94.433Å b: 94.433Å c: 153.707Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.205 0.223
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

Helicobacter pylori Virulence Factors-Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment.
Baj et al. (2020)
9 more

1 mention without citation

The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
Bonsor et al. (2018)