› 6b29

X-ray diffraction
1.3Å resolution

Crystal structure of the second SH3 domain of STAC3 (309-364)

Released:
DOI: 10.2210/pdb6b29/pdb
PDB entry 6b29 coloured by chain, front view.
PDB entry 6b29 coloured by chain, side view.
PDB entry 6b29 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Wong King Yuen SM, Campiglio M, Tung CC, Flucher BE, Van Petegem F
Proc Natl Acad Sci U S A 114 E9520-E9528 (2017)
PMID: 29078335

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188627 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SH3 and cysteine-rich domain-containing protein 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 59 amino acids
Theoretical weight: 6.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96MF2 (Residues: 309-364; Coverage: 15%)
Gene name: STAC3
Sequence domains: Variant SH3 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2221
Unit cell:
a: 49.54Å b: 57.96Å c: 156.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.157 0.189
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Skeletal muscle CaV1.1 channelopathies.
Flucher BE. (2020)
8 more

2 mentions without citation

Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Wong King Yuen et al. (2017)
1 more