Function and Biology Details
Reactions catalysed:
Endopeptidase with a preference for cleavage when the P1 position is occupied by Glu-|- and the P1' position is occupied by Gly-|-
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
3C-like protease (preferred)
PDBe Complex ID:
PDB-CPX-102319 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3C-like protease
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 181 amino acids
Theoretical weight: 19.24 KDa
Source organism: Norovirus GII.4
Expression system: Escherichia coli BL21
UniProt:
Structure domains: Trypsin-like serine proteases
Length: 181 amino acids
Theoretical weight: 19.24 KDa
Source organism: Norovirus GII.4
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
A0A0K2E2J2 (Residues: 1009-1189; Coverage: 11%)
Structure domains: Trypsin-like serine proteases
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 21-ID-F
Spacegroup:
P32
Expression system: Escherichia coli BL21
