Function and Biology Details
Reactions catalysed:
S-adenosyl-L-methionine + adenine in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine in U6 snRNA
S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine in mRNA
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
RNA N6-adenosine-methyltransferase METTL16 (preferred)
PDBe Complex ID:
PDB-CPX-183225 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA N6-adenosine-methyltransferase METTL16
Molecule details ›
Chain: A
Length: 294 amino acids
Theoretical weight: 33.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains: RNA methyltransferase
Length: 294 amino acids
Theoretical weight: 33.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical:
Q86W50 (Residues: 1-291; Coverage: 52%)
Sequence domains: RNA methyltransferase
