Function and Biology Details
Reaction catalysed:
Degradation of insulin, glucagon and other polypeptides. No action on proteins.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Insulin-degrading enzyme (preferred)
PDBe Complex ID:
PDB-CPX-147045 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin-degrading enzyme
Molecule details ›
Chains: A, B
Length: 966 amino acids
Theoretical weight: 111.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 966 amino acids
Theoretical weight: 111.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P14735 (Residues: 46-1011; Coverage: 95%)
Sequence domains:
