› 6blh

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-230913 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fab CB017.5 light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 22.84 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Fab CB017.5 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 234 amino acids
Theoretical weight: 25.1 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Mature secreted glycoprotein G Chain: G
Molecule details ›
Chain: G
Length: 45 amino acids
Theoretical weight: 5.18 KDa
Source organism: Human respiratory syncytial virus (strain RSB6256)
Expression system: Not provided
UniProt:
  • Canonical: P27025 (Residues: 153-197; Coverage: 15%)
Gene name: G

Ligands and Environments

1 bound ligand:
Ligand EDO 1 x EDO
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 85.069Å b: 189.646Å c: 74.14Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.187 0.226
Expression systems:
  • Homo sapiens
  • Not provided

Quick links

Citations

14 review citations

Respiratory syncytial virus entry and how to block it.
Battles et al. (2019)
13 more

5 mentions without citation

Toward rational vaccine engineering.
Vishweshwaraiah et al. (2022)
4 more