› 6bli

X-ray diffraction
2.12Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-230914 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
CB002.5 Fab Heavy Chain Chains: A, D, G, J
Molecule details ›
Chains: A, D, G, J
Length: 231 amino acids
Theoretical weight: 24.61 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
CB002.5 Fab Light Chain Chains: B, E, H, K
Molecule details ›
Chains: B, E, H, K
Length: 215 amino acids
Theoretical weight: 23.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Mature secreted glycoprotein G Chains: C, F, I, L
Molecule details ›
Chains: C, F, I, L
Length: 45 amino acids
Theoretical weight: 5.18 KDa
Source organism: Human respiratory syncytial virus (strain RSB6256)
Expression system: Not provided
UniProt:
  • Canonical: P27025 (Residues: 153-197; Coverage: 15%)
Gene name: G

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PCA 4 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: C2
Unit cell:
a: 113.76Å b: 85.23Å c: 214.3Å
α: 90° β: 95.03° γ: 90°
R-values:
R R work R free
0.171 0.169 0.218
Expression systems:
  • Homo sapiens
  • Not provided

Quick links

Citations

15 review citations

Respiratory syncytial virus entry and how to block it.
Battles et al. (2019)
14 more

2 mentions without citation

Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
Jones et al. (2018)
1 more