› 6bma

X-ray diffraction
1.98Å resolution

The crystal structure of indole-3-glycerol phosphate synthase from Campylobacter jejuni subsp. jejuni NCTC 11168

Released:
DOI: 10.2210/pdb6bma/pdb
PDB entry 6bma coloured by chain, front view.
PDB entry 6bma coloured by chain, side view.
PDB entry 6bma coloured by chain, top view.
Source organism: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Entry authors: Tan K, Zhou M, Nocek B, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192897 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Indole-3-glycerol phosphate synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 261 amino acids
Theoretical weight: 29.89 KDa
Source organism: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9PI11 (Residues: 1-258; Coverage: 100%)
Gene names: Cj0498, trpC
Sequence domains: Indole-3-glycerol phosphate synthase
Structure domains: Aldolase class I

Ligands and Environments

6 bound ligands:
Ligand K 2 x K
Ligand CL 2 x CL
Ligand PO4 9 x PO4
Ligand EDO 1 x EDO
Ligand ACT 3 x ACT
Ligand FMT 1 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: R32
Unit cell:
a: 148.181Å b: 148.181Å c: 149.947Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.196
Expression system: Escherichia coli

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