› 6bno

Electron Microscopy
5.5Å resolution

Structure of bare actin filament

Released:
DOI: 10.2210/pdb6bno/pdb
PDB entry 6bno coloured by chain, front view.
PDB entry 6bno coloured by chain, side view.
PDB entry 6bno coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity.
Gurel PS, Kim LY, Ruijgrok PV, Omabegho T, Bryant Z, Alushin GM
Elife 6 (2017)
PMID: 29199952
Related structures: EMD-7115

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159339 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 373 amino acids
Theoretical weight: 41.56 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 1-373; Coverage: 99%)
Gene names: ACTA, ACTA1
Sequence domains: Actin

Ligands and Environments

2 bound ligands:
Ligand MG 8 x MG
Ligand ADP 8 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.5Å
Relevant EMDB volumes: EMD-7115

Quick links

Citations

6 review citations

Towards a structural understanding of the remodeling of the actin cytoskeleton.
Merino et al. (2020)
5 more

11 mentions without citation

Protein Assembly by Design.
Zhu et al. (2021)
10 more