6bnq

Electron Microscopy
5.5Å resolution

CryoEM structure of Myosin VI-Actin complex in the ADP state

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetradecamer (preferred)
PDBe Complex ID:
PDB-CPX-159340 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Unconventional myosin-VI Chains: I, J, K, L, M, N
Molecule details ›
Chains: I, J, K, L, M, N
Length: 704 amino acids
Theoretical weight: 79.84 KDa
Source organism: Sus scrofa
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q29122 (Residues: 2-706; Coverage: 56%)
Gene name: MYO6
Sequence domains: Myosin head (motor domain)
Actin, alpha skeletal muscle Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 373 amino acids
Theoretical weight: 41.56 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 1-373; Coverage: 99%)
Gene names: ACTA, ACTA1
Sequence domains: Actin

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.5Å
Relevant EMDB volumes: EMD-7117
Expression system: Spodoptera frugiperda